Defensive publication

ABSTRACT

WITH ISOCYANIC ACID IN AN AQUEOUS MEDIUM OPTIONALLY CONTAINING UP TO 50% OF A NONREACTIVE ORGANIC LIQUID, AT A TEMPERATURE BETWEEN THE FREEZING POINT AND BOILING POINT OF THE REACTION MASS (USUALLY BETWEEN -15* C. AND 80* C.), IMPROVED YIELDS ARE OBTAINED BY MAINTAINING THE PH BETWEEN 1.5 AND 5.0, PREFERABLY BETWEEN 2.5 AND 4.5, MOST PREFERABLY BETWEEN 3.5 AND 4.0. THE ISOCYANIC ACID CAN BE GENERATED IN SITU BY CONCURRENT ADDITION OF AN ALKALI METAL CYANATE SUCH AS SODIUM CYANATE AND A MINERAL ACID SUCH AS H2SO4 TO THE REACTION MASS. IN THE PREPARATION OF THIOLHYDROXAMATE CARBAMATES OF THE FORMULA:   R1-(R2-S-)C=N-OOC-NH2   WHEREIN R1 IS METHYL, ETHYL, METHOXYMETHYL OR (METHYLTHIO) METHYL; AND R2 IS METHYL, ETHYL OR PROPYL; BY REACTION OF A THIOLHYDROXAMATE ESTER OF THE FORMULA:   R1-C(=N-OH)-S-R2

DEFENSIVE PUBLICATION UNITED STATES PATENT OFFICE Published at therequest of the applicant or owner in accordance with the Notice of Dec.16, 1969, 869 0.G. 687. The abstracts of. Defensive Publicationapplications are identified by distinctly numbered series and arearranged chronologically. The bending at each abstract indicates thenumber of pages oi. specification, including claims and sheets ofdrawings contained in the application as originally tiled. The flies ofthese applications are available to the public-for inspection andreproduction may be purchased for 30 cents a sheet.

Defensive Publication applications have not been examined as to themerits of alleged invention. The Patent Oilice makes no assertion as tothe novelty oi. the disclosed subject matter;

PUBLISHED MARCH 27, 1973 T908,004 PREPARATION OF THIOLHYDROXAMATECARBAMATES Earl W. Cummins, Oak Lane Manor, 2410 Shelipot Drive,Wilmington, Del. 19803 Continuation of application Ser. No. 872,725,Oct. 30, 1969. This application Oct. 7, 1971, Ser. No. 187,549 Int. Cl.C07c 119/00 US. Cl. 260453 R No Drawing. 15 Pages Specification In thepreparation of thiolhydroxarnate carbamates of the formula:

N3CNH2 i S a I wherein R is methyl, ethyl, methoxymethyl or (methylthio)methyl; and

R is methyl, ethyl or propyl;

by reaction of a thiolhydroxamate ester of the formula:

